The role of research in an academic institution is significant for its sustainability and development, and it is imperative to have knowledge-driven growth based on innovation. The main objective of this study was to find out the factors associated with research and productivity among faculty of higher education institutions. Descriptive correlational research method was used consisting of 232 regular faculty members among four campuses of an state University in Laguna, Philippines. The perceived level of self- motivation of the respondents on knowledge and skills, ability and interest, motivation and drive is “very high”; perceived level of institutional support system for research among faculty on policies and guidelines, promotion and incentives, research program, budgeting and external sourcing/funding is “highly evident”; perceived level of research- working environment, is “very highly evident”; perceived level of research productivity for research reveals that the research productivity is “very high” . Faculty’s research productivity is significantly predicted by self-motivation, an institutional support system for research; and research working environment; teacher’s perceived self-motivation mediated with the institutional support system and the faculty’s research productivity; teacher’s perceived self-motivation mediated with the research working environment and to the faculty’s research productivity. ANOVA result revealed that there is no significant difference occurred in the perceptions of the respondents on self-motivation, institutional support system for research, research working environment and research productivity when grouped according to their University Campus.